US researchers are hopeful that nanotechnology can be used to mobilise the
body's own healing abilities to repair or regenerate damaged cells.
Dr Samuel I Stupp, director of the
Institute
of Bionanotechnology in Medicine at
Northwestern
University, is combining nanotechnology and biology.
He has demonstrated how paralysed lab mice with spinal cord injuries can
regain the ability to walk using their hind limbs six weeks after a simple
injection of a purpose-designed nano-material.
"By injecting molecules that were designed to self-assemble into
nanostructures in the spinal tissue, we have been able to rescue and regrow
rapidly damaged neurons," said Dr Stupp.
"The nano-fibres, thousands of times thinner than a human hair, are the key
to not only preventing the formation of harmful scar tissue which inhibits
spinal cord healing, but to stimulating the body into regenerating lost or
damaged cells."
Dr Stupp's work hinges on self-assembly, a fundamental area of nanotechnology
that he believes will ultimately enable medical researchers to tailor patient
treatments in previously unimaginable ways.
The team designed molecules with the capacity to self-assemble into
nano-fibres once injected into the body with a syringe.
When the nano-fibres form they can be immobilised in an area of tissue where
it is necessary to activate some biological process, for example saving damaged
cells or regenerating differentiated cells from stem cells.
The researchers believe that this work also has implications for diseases
such as Parkinson's and Alzheimer's in which key brain cells stop working
properly.
"This research provides an early glimpse into the new and exciting places
where nanotechnology can take us," said David Rejeski, director of the
Project
on Emerging Nanotechnologies.
Comments
Have your say on this article